Overview of the Impact of Pathogenic LRRK2 Mutations in Parkinson’s Disease
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DOI: 10.3390/biom13050845
Abstract: Leucine-rich repeat kinase 2 (LRRK2) is a large protein kinase that physiologically phosphorylates and regulates the function of several Rab proteins. LRRK2 is genetically implicated in the pathogenesis of both familial and sporadic Parkinson’s disease… read more here.
Keywords: pathogenic mutations; parkinson disease; lrrk2 mutations; lrrk2 ... See more keywords