Comparison of CT radiogenomic and clinical characteristics between EGFR and KRAS mutations in lung adenocarcinomas.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical radiology"
DOI: 10.1016/j.crad.2018.01.009
Abstract: AIM To compare computed tomography (CT) radiogenomic and clinical characteristics between patients with epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) mutations in lung adenocarcinomas. MATERIALS AND METHODS This study was… read more here.
Keywords: egfr kras; radiogenomic clinical; mutations lung; lung adenocarcinomas ... See more keywords
Genotyping of common EGFR mutations in lung cancer patients by electrochemical biosensor.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2017.12.015
Abstract: In this study, we constructed a sandwich-type biosensor to identify six common types of mutations in exon 19 of the epidermal growth factor receptor (EGFR) gene, and tested them using tissue samples from patients with… read more here.
Keywords: egfr mutations; biosensor; mutations lung; lung cancer ... See more keywords
Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13732-y
Abstract: Reducing or eliminating persistent disparities in lung cancer incidence and survival has been challenging because our current understanding of lung cancer biology is derived primarily from populations of European descent. Here we show results from… read more here.
Keywords: among african; jak2 mutations; mutations lung; african americans ... See more keywords
Significance of testing for TP53 gene mutations in lung adenocarcinoma using targeted gene sequencing.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2018.10.66
Abstract: Randomized clinical trials have demonstrated the positive effects of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) for patients with advanced or recurrent lung adenocarcinomas harboring EGFR gene mutations (1-3). Detecting cancer-specific gene mutations and exploring… read more here.
Keywords: gene mutations; mutations lung; significance testing; tp53 gene ... See more keywords
Analysis of Fifty Hotspot Mutations of Lung Squamous Cell Carcinoma in Never-smokers
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Korean Medical Science"
DOI: 10.3346/jkms.2017.32.3.415
Abstract: Smoking is the major risk factor for lung squamous cell carcinoma (SCC), although a small number of lung SCCs occurs in never-smokers. The purpose of this study was to compare 50 hotspot mutations of lung… read more here.
Keywords: never smokers; squamous cell; hotspot mutations; mutations lung ... See more keywords
New Actions on Actionable Mutations in Lung Cancers
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15112917
Abstract: Actionable mutations refer to DNA alterations that, if detected, would be expected to affect patients’ response to treatments [...] read more here.
Keywords: cancers new; actionable mutations; new actions; actions actionable ... See more keywords
Germline EGFR mutations in lung cancer (Review)
Sign Up to like & getrecommendations! Published in 2023 at "Oncology Letters"
DOI: 10.3892/ol.2023.13868
Abstract: Lung cancer is the leading cause of cancer-related death and familial lung cancer is a potential contributing factor. Epidermal growth factor receptor (EGFR) mutations are important events in carcinogenesis. The present study summarized the common… read more here.
Keywords: lung cancer; mutations lung; egfr mutations; germline egfr ... See more keywords