Mutations of MAP2K1 are frequent in pediatric-type follicular lymphoma and result in ERK pathway activation.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2017-03-776278
Abstract: Pediatric-type follicular lymphoma (PTFL) is a B-cell lymphoma with distinctive clinicopathological features. Recently, recurrent genetic alterations of potential importance for its pathogenesis that disrupt pathways associated with the germinal center reaction (TNFRSF14, IRF8), immune escape… read more here.
Keywords: mutations map2k1; type follicular; follicular lymphoma; pediatric type ... See more keywords