Effect of KRAS mutations and p53 expression on the postoperative prognosis of patients with colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1905
Abstract: In the occurrence and development of colorectal cancer, p53 is an important regulator downstream of the MAPK signaling pathway and plays an important role in inhibiting abnormal proliferation signals generated by KRAS mutations. The purpose… read more here.
Keywords: kras mutations; p53 expression; colorectal cancer; mutations p53 ... See more keywords
The Evolution of Tumor Formation in Humans and Mice with Inherited Mutations in the p53 Gene.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2017_5
Abstract: While tumors are very heterogeneous in their origins, mutations in the p53 gene and inactivation of p53 gene functions are the most common feature that predispose to the formation of cancers in humans. Inherited p53… read more here.
Keywords: inherited mutations; p53 gene; mutations p53; p53 ... See more keywords