Dual activating FGFR1 mutations in pediatric pilomyxoid astrocytoma
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1597
Abstract: Pilomyxoid astrocytomas are an aggressive subtype of astrocytoma, not graded by WHO, frequently located in hypothalamic/chiasmatic region, affecting diencephalic structures, and characterized by shorter survival and high recurrence rates. Pilomyxoid astrocytoma management remains controversial, with… read more here.
Keywords: dual activating; astrocytoma; pilomyxoid astrocytoma; mutations pediatric ... See more keywords
PD-L1 and PD-L2 Mutations in Pediatric Hodgkin Lymphoma: Do They Have Any Prognostic Significance?
Sign Up to like & getrecommendations! Published in 2020 at "Fetal and pediatric pathology"
DOI: 10.1080/15513815.2020.1764680
Abstract: Background: Reed-Sternberg cells can escape from the immune system by enhancement of the expression of PD-L1 and PD-L2. Objectives: The aim of the present study was to investigate the significance PD-L1 and PD-L2 gene mutations… read more here.
Keywords: hodgkin lymphoma; mutations pediatric; significance; pediatric hodgkin ... See more keywords
BCOR, BCORL1, and BCL6 Mutations in Pediatric Leukemias
Sign Up to like & getrecommendations! Published in 2025 at "Cancers"
DOI: 10.3390/cancers17152443
Abstract: Simple Summary Genetic changes play an important role in the development of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Some rare genetic mutations, specifically in the BCOR and BCORL1 genes, have been found in… read more here.
Keywords: mutations pediatric; bcor bcorl1; bcorl1 bcl6; bcl6 mutations ... See more keywords