Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis
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DOI: 10.1038/s41598-018-22883-9
Abstract: Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug, resistance to which occurs primarily due to mutations in pncA (Rv2043c) that encodes the pyrazinamidase enzyme responsible for conversion of pro-drug PZA into its active form. Previous… read more here.
Keywords: among various; tuberculosis; mutations pnca; lineages mycobacterium ... See more keywords