STK11/LKB1 co-mutations to predict for de novo resistance to PD-1/PD-L1 axis blockade in KRAS-mutant lung adenocarcinoma.
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DOI: 10.1200/jco.2017.35.15_suppl.9016
Abstract: 9016Background: Identification of molecular predictors of response to PD-1/PD-L1 inhibitors is critical in order to maximize their therapeutic potential. We previously reported that KRAS-mutant lung adenocarcinomas (LUAC) with co-occurring genetic events in STK11/LKB1(KL) or TP53… read more here.
Keywords: lkb1 mutations; mutations predict; stk11 lkb1; mutant lung ... See more keywords