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Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.05.003
Abstract: SUMMARY Cells have evolved quality control pathways to prevent the accumulation of improperly localized proteins, which are often toxic. One of these pathways, regulation of aberrant protein production (RAPP), recognizes aberrant secretory proteins during translation…
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Keywords:
progranulin disrupt;
signal sequence;
grn;
sequence mutations ... See more keywords