ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.02.040
Abstract: Melanomas accumulate a high burden of mutations that could potentially generate neoantigens, yet somehow suppress the immune response to facilitate continued growth. In this study, we identify a subset of human melanomas that have loss-of-function… read more here.
Keywords: melanoma; mutations promote; atr mutations; immune microenvironment ... See more keywords
TERT Promoter Mutations Promote Immortalization and Genomic Instability.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2017-161
Abstract: TERT promoter mutations may induce early and late tumorigenesis by separate mechanisms. read more here.
Keywords: promote immortalization; mutations promote; promoter mutations; tert promoter ... See more keywords