Human Cancer-Associated Mutations of SF3B1 Lead to a Splicing Modification of Its Own RNA
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DOI: 10.3390/cancers12030652
Abstract: Deregulation of pre-mRNA splicing is observed in many cancers and hematological malignancies. Genes encoding splicing factors are frequently mutated in myelodysplastic syndromes, in which SF3B1 mutations are the most frequent. SF3B1 is an essential component… read more here.
Keywords: sf3b1; associated mutations; human cancer; mutations sf3b1 ... See more keywords