Articles with "mutations tp53" as a keyword



Molecular: Genetic analysis of uterine carcinosarcomas

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Published in 2019 at "Annals of Oncology"

DOI: 10.1093/annonc/mdz413.081

Abstract: Abstract Background Tissue precursors of uterine carcinosarcomas remain unknown, therefore targeted therapy has not been determined. Methods This research is based on the investigation of formalin‐fixed, paraffin‐embedded tissue blocks from 17 women undergoing primary surgical… read more here.

Keywords: carcinosarcomas; mutations tp53; analysis; detected tumours ... See more keywords

Prognostic value of KRAS mutations, TP53 mutations and PD-L1 expression among lung adenocarcinomas treated with immunotherapy

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Published in 2022 at "Journal of Clinical Pathology"

DOI: 10.1136/jcp-2022-208574

Abstract: Aims The aim of this study was to investigate the association between oncogenic alterations and programmed cell death ligand 1 (PD-L1) expression in lung adenocarcinomas, as well as the prognostic value of KRAS and/or TP53… read more here.

Keywords: mutations tp53; mutations expression; treated immunotherapy; lung adenocarcinomas ... See more keywords

The impact of mutations on TP53 protein and MicroRNA expression in HNSCC: Novel insights for diagnostic and therapeutic strategies

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Published in 2025 at "PLOS One"

DOI: 10.1371/journal.pone.0307859

Abstract: The tumor suppressor protein p53 (TP53) is frequently mutated in various types of human malignancies, including HNSCC, which affects tumor growth, prognosis, and treatment. Gaining insight into the impact of TP53 mutations in HNSCC is… read more here.

Keywords: mutations tp53; r280g; q136h; hnscc ... See more keywords