Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors
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DOI: 10.1136/annrheumdis-2017-212401
Abstract: Objectives To characterise the clinical features, immune manifestations and molecular mechanisms in a recently described autoinflammatory disease caused by mutations in TRNT1, a tRNA processing enzyme, and to explore the use of cytokine inhibitors in… read more here.
Keywords: processing causes; processing; tnf; trna processing ... See more keywords