Mutations Utilize Dynamic Allostery to Confer Resistance in TEM-1 β-lactamase
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DOI: 10.3390/ijms19123808
Abstract: β-lactamases are enzymes produced by bacteria to hydrolyze β-lactam antibiotics as a common mechanism of resistance. Evolution in such enzymes has been rendering a wide variety of antibiotics impotent, therefore posing a major threat. Clinical… read more here.
Keywords: utilize dynamic; dynamic coupling; tem lactamase; resistance ... See more keywords