The complex nature of CXCR4 mutations in WHIM syndrome
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DOI: 10.3389/fimmu.2024.1406532
Abstract: Heterozygous autosomal dominant mutations in the CXCR4 gene cause WHIM syndrome, a severe combined immunodeficiency disorder. The mutations primarily affect the C-terminal region of the CXCR4 chemokine receptor, specifically several potential phosphorylation sites critical for… read more here.
Keywords: mutations whim; cxcr4; nature cxcr4; whim syndrome ... See more keywords