Biochemical characterization of mismatch-binding protein MutS1 and nicking endonuclease MutL from a euryarchaeon Methanosaeta thermophila.
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DOI: 10.1016/j.dnarep.2019.01.005
Abstract: In eukaryotes and most bacteria, the MutS1/MutL-dependent mismatch repair system (MMR) corrects DNA mismatches that arise as replication errors. MutS1 recognizes mismatched DNA and stimulates the nicking endonuclease activity of MutL to incise mismatch-containing DNA.… read more here.
Keywords: endonuclease; nicking endonuclease; muts1 mutl; mutl ... See more keywords