Articles with "mutual exclusivity" as a keyword



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Twelve-month-olds disambiguate new words using mutual-exclusivity inferences

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Published in 2021 at "Cognition"

DOI: 10.1016/j.cognition.2021.104691

Abstract: Representing objects in terms of their kinds enables inferences based on the long-term knowledge made available through kind concepts. For example, children readily use lexical knowledge linked to familiar kind concepts to disambiguate new words… read more here.

Keywords: mutual exclusivity; kind; new words; exclusivity inferences ... See more keywords
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OMEN: network-based driver gene identification using mutual exclusivity

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Published in 2022 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btac312

Abstract: MOTIVATION Network-based driver identification methods that can exploit mutual exclusivity typically fail to detect rare drivers because of their statistical rigor. Propagation-based methods in contrast allow recovering rare driver genes, but the interplay between network… read more here.

Keywords: network; based driver; network based; mutual exclusivity ... See more keywords
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A heuristic algorithm solving the mutual-exclusivity-sorting problem

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Published in 2023 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btad016

Abstract: Abstract Motivation Binary (or Boolean) matrices provide a common effective data representation adopted in several domains of computational biology, especially for investigating cancer and other human diseases. For instance, they are used to summarize genetic… read more here.

Keywords: mutual exclusivity; exclusivity; exclusivity sorting; sorting problem ... See more keywords
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A greedy approach for mutual exclusivity analysis in cancer study.

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Published in 2021 at "Biostatistics"

DOI: 10.1093/biostatistics/kxab004

Abstract: The main challenge in cancer genomics is to distinguish the driver genes from passenger or neutral genes. Cancer genomes exhibit extensive mutational heterogeneity that no two genomes contain exactly the same somatic mutations. Such mutual… read more here.

Keywords: cancer; mutual exclusivity; analysis; greedy approach ... See more keywords
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gcMECM: graph clustering of mutual exclusivity of cancer mutations

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Published in 2021 at "BMC Bioinformatics"

DOI: 10.1186/s12859-021-04505-w

Abstract: Background Next-generation sequencing platforms allow us to sequence millions of small fragments of DNA simultaneously, revolutionizing cancer research. Sequence analysis has revealed that cancer driver genes operate across multiple intricate pathways and networks with mutations… read more here.

Keywords: cancer; mutual exclusivity; clustering mutual; gcmecm graph ... See more keywords