Overcoming PEG─Protein Mutual Repulsion to Improve the Efficiency of PEGylation.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01192
Abstract: Bioconjugation reactions, such as protein PEGylation, generally require excess reagents because of their inefficiency. Intriguingly, few reports have investigated the fundamental causes of this inefficiency. This study demonstrates that the excluded volume effect (EVE)─caused by… read more here.
Keywords: reactive mpeg; mpeg; mutual repulsion; pegylation ... See more keywords