Ca2+ functions as a molecular switch that controls the mutually exclusive complex formation of pyridoxal phosphatase with CIB1 or calmodulin
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13795
Abstract: Pyridoxal 5′‐phosphate (PLP) is an essential cofactor for neurotransmitter metabolism. Pyridoxal phosphatase (PDXP) deficiency in mice increases PLP and γ‐aminobutyric acid levels in the brain, yet how PDXP is regulated is unclear. Here, we identify… read more here.
Keywords: phosphatase; mutually exclusive; pdxp; pyridoxal phosphatase ... See more keywords
Resolving the Mutually Exclusive Immune Responses of Chitosan with Nanomechanics and Immunological Assays
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102667
Abstract: Multifaceted functions displayed by both pro‐ and anti‐inflammatory properties of chitosan hinder its effective development as an immunomodulatory agent. Herein, the contributions of the bending stiffness of chitosan with regard to its immune regulatory properties… read more here.
Keywords: anti inflammatory; mutually exclusive; resolving mutually; immunological assays ... See more keywords
Integrated multi‐omics data analyses for exploring the co‐occurring and mutually exclusive gene alteration events in colorectal cancer
Sign Up to like & getrecommendations! Published in 2020 at "Human Mutation"
DOI: 10.1002/humu.24059
Abstract: Co‐occurring and mutually exclusive gene alteration events are helpful for understanding carcinogenesis but systematic screening for such events is quite limited. We conducted pairwise screening tests to identify “hit pairs” in colorectal cancer (CRC) by… read more here.
Keywords: occurring mutually; mutually exclusive; alteration events; gene alteration ... See more keywords
Mutually exclusive alternative splicing of pre‐mRNAs
Sign Up to like & getrecommendations! Published in 2018 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1468
Abstract: Pre‐mRNA alternative splicing is an important mechanism used to expand protein diversity in higher eukaryotes, and mutually exclusive splicing is a specific type of alternative splicing in which only one of the exons in a… read more here.
Keywords: exclusive alternative; splicing pre; exclusive splicing; mutually exclusive ... See more keywords
Plasma protein biomarkers and their association with mutually exclusive cardiovascular phenotypes: the FIBRO-TARGETS case–control analyses
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Research in Cardiology"
DOI: 10.1007/s00392-019-01480-4
Abstract: Background Hypertension, obesity and diabetes are major and potentially modifiable “risk factors” for cardiovascular diseases. Identification of biomarkers specific to these risk factors may help understanding the underlying pathophysiological pathways, and developing individual treatment. Methods… read more here.
Keywords: fibro targets; hypertension; mutually exclusive; obesity ... See more keywords
Artificial two-dimensional polar metal by charge transfer to a ferroelectric insulator
Sign Up to like & getrecommendations! Published in 2019 at "Communications Physics"
DOI: 10.1038/s42005-019-0227-4
Abstract: Integrating multiple properties in a single system is crucial for the continuous developments in electronic devices. However, some physical properties are mutually exclusive in nature. Here, we report the coexistence of two seemingly mutually exclusive… read more here.
Keywords: 2sr0 8tio3; two dimensional; artificial two; dimensional polar ... See more keywords
High‐resolution melting and immunohistochemical analysis efficiently detects mutually exclusive genetic alterations of adamantinomatous and papillary craniopharyngiomas
Sign Up to like & getrecommendations! Published in 2018 at "Neuropathology"
DOI: 10.1111/neup.12408
Abstract: Craniopharyngioma consists of adamantinomatous and papillary subtypes. Recent genetic analysis has demonstrated that the two subtypes are different, not only in clinicopathological features, but also in molecular oncogenesis. Papillary craniopharyngioma (pCP) is characterized by a… read more here.
Keywords: braf v600e; analysis; genetic alterations; mutually exclusive ... See more keywords
gcMECM: graph clustering of mutual exclusivity of cancer mutations
Sign Up to like & getrecommendations! Published in 2021 at "BMC Bioinformatics"
DOI: 10.1186/s12859-021-04505-w
Abstract: Background Next-generation sequencing platforms allow us to sequence millions of small fragments of DNA simultaneously, revolutionizing cancer research. Sequence analysis has revealed that cancer driver genes operate across multiple intricate pathways and networks with mutations… read more here.
Keywords: cancer; mutual exclusivity; clustering mutual; gcmecm graph ... See more keywords
Mutually exclusive amino acid residues of L13a are responsible for its ribosomal incorporation and translational silencing leading to resolution of inflammation.
Sign Up to like & getrecommendations! Published in 2019 at "RNA"
DOI: 10.1261/rna.071118.119
Abstract: Eukaryotic ribosomal protein L13a is a member of the conserved universal ribosomal uL13 protein family. Structurally, L13a is distinguished from its prokaryotic counterparts by the presence of a ~55 amino acid-long C-terminal α-helical extension. The… read more here.
Keywords: amino; amino acid; translational silencing; incorporation ... See more keywords
A mutually-exclusive binary cross tagging framework for joint extraction of entities and relations
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DOI: 10.1371/journal.pone.0260426
Abstract: Joint extraction from unstructured text aims to extract relational triples composed of entity pairs and their relations. However, most existing works fail to process the overlapping issues that occur when the same entities are utilized… read more here.
Keywords: exclusive binary; cross tagging; joint extraction; framework ... See more keywords
Assessing trade-offs in avian behaviour using remotely collected data from a webcam
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DOI: 10.1371/journal.pone.0271257
Abstract: Individual animals engage in many behaviours which are mutually exclusive, and so where individuals increase the duration of time spent on one type of behavioural activity, this must be offset by a corresponding decrease in… read more here.
Keywords: remotely collected; time; aggression; behaviour ... See more keywords