Transcriptional Tuning of Mevalonate Pathway Enzymes to Identify the Impact on Limonene Production in Escherichia coli
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DOI: 10.1021/acsomega.2c00483
Abstract: Heterologous production of limonene in microorganisms through the mevalonate (MVA) pathway has traditionally imposed metabolic burden and reduced cell fitness, where imbalanced stoichiometries among sequential enzymes result in the accumulation of toxic intermediates. Although prior… read more here.
Keywords: mva pathway; escherichia coli; limonene; production ... See more keywords
Transcriptomic profiling reveals MEP pathway contributing to ginsenoside biosynthesis in Panax ginseng
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DOI: 10.1186/s12864-019-5718-x
Abstract: BackgroundPanax ginseng C. A. Mey is one of famous medicinal herb plant species. Its major bioactive compounds are various ginsenosides in roots and rhizomes. It is commonly accepted that ginsenosides are synthesized from terpene precursors,… read more here.
Keywords: ginseng; mep pathway; mva pathway; ginsenoside biosynthesis ... See more keywords
Synthesis of cembratriene-ol and cembratriene-diol in yeast via the MVA pathway
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DOI: 10.1186/s12934-021-01523-4
Abstract: Background Cembranoids are one kind of diterpenoids with multiple biological activities. The tobacco cembratriene-ol (CBT-ol) and cembratriene-diol (CBT-diol) have high anti-insect and anti-fungal activities, which is attracting great attentions for their potential usage in sustainable… read more here.
Keywords: cembratriene; mva pathway; diol; cbt ... See more keywords
Biosynthesis of Isoprene Units in Euphorbia lathyris Laticifers vs. Other Tissues: MVA and MEP Pathways, Compartmentation and Putative Endophytic Fungi Contribution
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DOI: 10.3390/molecules24234322
Abstract: Euphorbia species are characterized by a net of laticifers producing large amounts of triterpenes. These hydrocarbon-like metabolites can be converted into fuel by the methods of the oil industry. Euphorbia lathyris is easily grown at… read more here.
Keywords: biosynthesis isoprene; mva pathway; contribution; latex triterpenes ... See more keywords