Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic Tolerance.
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DOI: 10.1021/acschembio.6b01139
Abstract: Pseudomonas aeruginosa is an important nosocomial pathogen that is frequently recalcitrant to available antibiotics, underlining the urgent need for alternative therapeutic options against this pathogen. Targeting virulence functions is a promising alternative strategy as it… read more here.
Keywords: mvfr; pseudomonas aeruginosa; polypharmacology; mvfr regulon ... See more keywords