Author update: Sarcoplasmic MxA expression: A valuable marker of dermatomyositis
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DOI: 10.1212/wnl.0000000000004102
Abstract: Soon after our article published,1 we learned the sale of the myxovirus resistance A (MxA) polyclonal antibodies used in the study (Mx1/2/3 [H-285], sc-50509, Santa Cruz Biotechnology, Dallas, TX) had been discontinued. Furthermore, we received… read more here.
Keywords: sarcoplasmic mxa; mxa; mxa expression; dermatomyositis ... See more keywords
Vaccinia virus and Cowpox virus are not susceptible to the interferon-induced antiviral protein MxA
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DOI: 10.1371/journal.pone.0181459
Abstract: MxA protein is expressed in response to type I and type III Interferon and constitute an important antiviral factor with broad antiviral activity to diverse RNA viruses. In addition, some studies expand the range of… read more here.
Keywords: interferon; vaccinia virus; activity; mxa ... See more keywords
Rapid Reversible Osmoregulation of Cytoplasmic Biomolecular Condensates of Human Interferon-α-Induced Antiviral MxA GTPase
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DOI: 10.3390/ijms232112739
Abstract: Cellular and tissue-level edema is a common feature of acute viral infections such as covid-19, and of many hyponatremic hypoosmolar disorders. However, there is little understanding of the effects of cellular edema on antiviral effector… read more here.
Keywords: mxa; reversible osmoregulation; min; rapid reversible ... See more keywords
Increased Polymerase Activity of Zoonotic H7N9 Allows Partial Escape from MxA
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DOI: 10.3390/v14112331
Abstract: The interferon-induced myxovirus resistance protein A (MxA) is a potent restriction factor that prevents zoonotic infection from influenza A virus (IAV) subtype H7N9. Individuals expressing antivirally inactive MxA variants are highly susceptible to these infections.… read more here.
Keywords: mxa escape; rag2; h7n9; escape mxa ... See more keywords