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Immunization of mice with LRP4 induces myasthenia similar to MuSK-associated myasthenia gravis

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Published in 2017 at "Experimental Neurology"

DOI: 10.1016/j.expneurol.2017.08.006

Abstract: Since the first report of experimental animal models of myasthenia gravis (MG) with autoantibodies against low-density lipoprotein receptor-related protein 4 (LRP4), there have not been any major reports replicating the pathogenicity of anti-LRP4 antibodies (Abs).… read more here.

Keywords: immunization; myasthenia gravis; mice; lrp4 ... See more keywords