Modulation of Myb‐induced NF‐kB ‐STAT3 signaling and resulting cisplatin resistance in ovarian cancer by dietary factors
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28715
Abstract: c‐Myb regulates tumorigenesis in multiple cancers. Here we show, for the first time, the mechanism of c‐Myb‐mediated proliferation, invasion, and drug resistance in ovarian cancer (OC), the most lethal gynecological cancer, and a comparative analyses… read more here.
Keywords: resistance ovarian; proliferation invasion; ovarian cancer; myb ... See more keywords
An R3-MYB gene of Phalaenopsis, MYBx1, represses anthocyanin accumulation
Sign Up to like & getrecommendations! Published in 2019 at "Plant Growth Regulation"
DOI: 10.1007/s10725-019-00493-3
Abstract: Anthocyanins are secondary metabolites that are involved in providing flower petal pigmentation. In plants, anthocyanin synthesis is regulated positively by a conserved MYB-bHLH-WD40 (MBW) complex and negatively by repressors. We isolated a repressor of anthocyanin… read more here.
Keywords: anthocyanin synthesis; expression; myb; phalaenopsis ... See more keywords
A R2R3-type MYB transcription factor gene from soybean, GmMYB12, is involved in flavonoids accumulation and abiotic stress tolerance in transgenic Arabidopsis
Sign Up to like & getrecommendations! Published in 2019 at "Plant Biotechnology Reports"
DOI: 10.1007/s11816-019-00530-7
Abstract: The R2R3-type MYB transcription factors have been shown to increase flavonoids accumulation by regulating the expression of key enzyme genes related to flavonoid biosynthesis pathway. However, the roles and underlying mechanisms of the soybean GmMYB12… read more here.
Keywords: tolerance; r2r3 type; flavonoids accumulation; myb ... See more keywords
DNA-binding induced conformational change of c-Myb R2R3 analyzed using diffracted X-ray tracking.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.06.025
Abstract: Previous structural analyses have shown that R2R3, the minimum unit of the DNA-binding domain of the transcriptional factor c-Myb, is largely flexible in solution, and changes to a more rigid structure upon DNA binding. In… read more here.
Keywords: diffracted ray; dna; using diffracted; myb ... See more keywords
Genome-wide analysis and expression profiles of the StR2R3-MYB transcription factor superfamily in potato (Solanum tuberosum L.).
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.01.167
Abstract: MYB transcription factors comprise one of the largest families in plant kingdom, which play a variety of functions in plant developmental processes and defence responses, the R2R3-MYB members are the predominant form found in higher… read more here.
Keywords: analysis; str2r3 myb; myb; gene ... See more keywords
PatSWC4, a methyl jasmonate-responsive MYB (v-myb avian myeloblastosis viral oncogene homolog)-related transcription factor, positively regulates patchoulol biosynthesis in Pogostemon cablin
Sign Up to like & getrecommendations! Published in 2020 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2020.112672
Abstract: Abstract Patchoulol, the major active ingredient in Pogostemon cablin (Blanco) Benth., has considerable clinical and industrial value. A number of genes that participate in the patchoulol biosynthesis pathway have been identified; however, little is known… read more here.
Keywords: patchoulol biosynthesis; cablin; myb; patswc4 ... See more keywords
Inducible disruption of the c-myb gene allows allogeneic bone marrow transplantation without irradiation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2018.03.016
Abstract: Allogeneic bone marrow (BM) transplantation enables the in vivo functional assessment of hematopoietic cells. As pre-conditioning, ionizing radiation is commonly applied to induce BM depletion, however, it exerts adverse effects on the animal and can… read more here.
Keywords: marrow transplantation; allogeneic bone; transplantation; myb ... See more keywords
TALEN-mediated biallelic inactivation of MYB in human embryonic stem cell lines WAe001-A-45 and WAe001-A-46.
Sign Up to like & getrecommendations! Published in 2020 at "Stem cell research"
DOI: 10.1016/j.scr.2020.101854
Abstract: MYB/c-MYB is a proto-oncogene encoding a helix-turn-helix transcription factor that plays a critical role in controlling proliferation and multilineage differentiation of hematopoietic progenitor and stem cells. Deregulation of MYB expression is associated with several types… read more here.
Keywords: cell lines; myb; stem; myb human ... See more keywords
In silico genome-wide identification, phylogeny and expression analysis of the R2R3-MYB gene family in Medicago truncatula
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Integrative Agriculture"
DOI: 10.1016/s2095-3119(16)61521-6
Abstract: Abstract The R2R3-MYB genes make up one of the largest transcription factor families in plants, and play regulatory roles in various biological processes such as development, metabolism and defense response. Although genome-wide analyses of this… read more here.
Keywords: analysis; family; r2r3 myb; myb ... See more keywords
Evolution of the R2R3-MYB gene family in six Rosaceae species and expression in woodland strawberry
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Integrative Agriculture"
DOI: 10.1016/s2095-3119(19)62818-2
Abstract: Abstract R2R3-MYB gene family play important roles in plants development, metabolism, and responses to various biotic and abiotic stresses. In this study, 838 R2R3-MYB genes were identified from six Rosaceae species, including 105 in woodland… read more here.
Keywords: rosaceae species; six rosaceae; myb genes; r2r3 myb ... See more keywords
The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb
Sign Up to like & getrecommendations! Published in 2018 at "Oncogene"
DOI: 10.1038/s41388-018-0490-y
Abstract: Overexpression of the oncogene MYBL2 (B-Myb) is associated with increased cell proliferation and serves as a marker of poor prognosis in cancer. However, the mechanism by which B-Myb alters the cell cycle is not fully… read more here.
Keywords: cell cycle; dream complex; myb;