Components from the Human c-myb Transcriptional Regulation System Reactivate Epigenetically Repressed Transgenes
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DOI: 10.3390/ijms21020530
Abstract: A persistent challenge for mammalian cell engineering is the undesirable epigenetic silencing of transgenes. Foreign DNA can be incorporated into closed chromatin before and after it has been integrated into a host cell’s genome. To… read more here.
Keywords: transcriptional regulation; epigenetic silencing; system; myb transcriptional ... See more keywords