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Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc4517
Abstract: Growth of pancreatic cancers with hemizygous chromosomal 17p loss of MYBBP1A can be preferentially targeted by PARP inhibitors. Here, we selectively target pancreatic ductal adenocarcinoma (PDAC) cells harboring a hemizygous gene essential for cell growth.…
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Keywords:
mybbp1a;
cancers hemizygous;
pancreatic cancers;
growth ... See more keywords