A novel DNA methylation 10-CpG prognostic signature of disease-free survival reveal that MYBL2 is associated with high risk in prostate cancer
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2020.1838280
Abstract: ABSTRACT Background Prostate cancer (PC) is the most common non-cutaneous malignancy among men in the western world. However, heterogeneity remains a pressing clinical problem. Research design and methods The least absolute shrinkage and selection operator… read more here.
Keywords: mybl2; prognostic signature; dna methylation; prostate cancer ... See more keywords
Pan-cancer analysis indicates that MYBL2 is associated with the prognosis and immunotherapy of multiple cancers as an oncogene.
Sign Up to like & getrecommendations! Published in 2021 at "Cell cycle"
DOI: 10.1080/15384101.2021.1982494
Abstract: MYBL2 has been demonstrated to be an oncogene in some cancers, but there is no pan-cancer analysis at the macro level. We used multiple online or offline bioinformatic tools to examine the effects of MYBL2… read more here.
Keywords: mybl2; pan cancer; cancer analysis; level ... See more keywords
Actin-binding Rho activating C-terminal like (ABRACL) transcriptionally regulated by MYB proto-oncogene like 2 (MYBL2) promotes the proliferation, invasion, migration and epithelial-mesenchymal transition of breast cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2056821
Abstract: Breast cancer is the most common malignant tumor in females with high incidence and mortality. Actin-binding Rho activating C-terminal like (ABRACL) was highly expressed in several cancers. We aimed to investigate the function and mechanism… read more here.
Keywords: cancer; cancer cells; breast cancer; abracl ... See more keywords
MYBL2 is a Novel Independent Prognostic Biomarker and Correlated with Immune Infiltrates in Prostate Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s351638
Abstract: Purpose MYB proto-oncogene like 2 (MYBL2) is a member of the MYB family of transcription factor genes and overexpressed in many cancers. We investigated the role of MYBL2 in the malignant progression of prostate cancer… read more here.
Keywords: immune infiltrates; pca; cancer; mybl2 ... See more keywords
Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma
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DOI: 10.2147/ott.s190145
Abstract: Background The MYBL2 gene, a highly conserved member of the Myb transcription-factor family, has been implicated in the genesis and progression of many types of tumors. Methods We analyzed the expression of MYBL2 and Ki67… read more here.
Keywords: expression; esophageal squamous; escc; mybl2 ... See more keywords
Downstream Regulatory Network of MYBL2 Mediating Its Oncogenic Role in Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.816070
Abstract: The transcription factor MYBL2 is widely expressed in proliferating cells. Aberrant expression of MYBL2 contributes to tumor malignancy and is associated with poor patient prognosis. However, the downstream transcriptional network that mediates its oncogenic properties… read more here.
Keywords: mybl2; cell; melanoma; patient ... See more keywords
Characterizing and Targeting Genes Regulated by Transcription Factor MYBL2 in Lung Adenocarcinoma Cells
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DOI: 10.3390/cancers14204979
Abstract: Simple Summary The clinical behavior and progression of lung cancer vary case by case. Therefore, understanding the factors that contribute to aggressive lung cancer cases is crucially needed. Previously, we showed that transcription factor MYBL2… read more here.
Keywords: mybl2; lung adenocarcinoma; transcription; lung ... See more keywords