E3 ubiquitin ligase FBW7Ī± inhibits cholangiocarcinoma cell proliferation by downregulating c-Myc and cyclin E.
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DOI: 10.3892/or.2017.5432
Abstract: FBW7 (F-box and WD repeat domain-containingĀ 7), also known as CDC4, AGO and SEL10, is the substrate recognition component of an evolutionary conserved SCF (complex of SKP1, CUL1 and F-box protein)-type E3 ubiquitin ligase. It is… read more here.
Keywords: cell proliferation; myc cyclin; fbw7; cca ... See more keywords