An early Myc‐dependent transcriptional program orchestrates cell growth during B‐cell activation
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DOI: 10.15252/embr.201947987
Abstract: Upon activation, lymphocytes exit quiescence and undergo substantial increases in cell size, accompanied by activation of energy‐producing and anabolic pathways, widespread chromatin decompaction, and elevated transcriptional activity. These changes depend upon prior induction of the… read more here.
Keywords: early myc; dependent transcriptional; activation; cell ... See more keywords
TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8+ T cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.913184
Abstract: T cell activation is dependent upon the integration of antigenic, costimulatory and cytokine-derived signals and the availability and acquisition of nutrients from the environment. Furthermore, T cell activation is accompanied by reprogramming of cellular metabolism… read more here.
Keywords: tcr; myc dependent; cell activation; tcr induced ... See more keywords
Hyperoxia Inhibits Proliferation of Retinal Endothelial Cells in a Myc-Dependent Manner
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DOI: 10.3390/life11070614
Abstract: Oxygen supplementation is necessary to prevent mortality in severely premature infants. However, the supraphysiological concentration of oxygen utilized in these infants simultaneously creates retinovascular growth attenuation and vasoobliteration that induces the retinopathy of prematurity. Here,… read more here.
Keywords: hyperoxia inhibits; proliferation; dependent manner; retinal endothelial ... See more keywords