Enhanced expression of Cyclin D1 and C-myc, a prognostic factor and possible mechanism for recurrence of papillary thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-61985-1
Abstract: A direct association has been shown between Cyclin D1 and C-myc gene expressions and the proliferation of human thyroid tumor cells. Our previous study showed that increased β catenin led to a reduction in disease-free… read more here.
Keywords: recurrence; cyclin myc; myc gene; cyclin ... See more keywords
MYC gene amplification by fluorescence in situ hybridization and MYC protein expression by immunohistochemistry in the diagnosis of cutaneous angiosarcoma: Systematic review and appropriate use criteria
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cutaneous Pathology"
DOI: 10.1111/cup.13912
Abstract: Secondary angiosarcoma (AS) most commonly follows breast cancer and includes postirradiation AS (PRAS) and lymphedema‐associated AS. The frequent amplification of MYC (8q24.21) in secondary AS and the rising incidence of PRAS and atypical vascular lesions… read more here.
Keywords: amplification fluorescence; fluorescence situ; myc gene; angiosarcoma ... See more keywords
Burkitt lymphoma: interpreting FISH testing for MYC gene rearrangements
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-246687
Abstract: Burkitt lymphoma is a highly aggressive B cell non-Hodgkin’s lymphoma characterised by translocation of MYC gene on chromosome 8. This translocation is usually detected by fluorescent in-situ hybridisation (FISH) studies as part of routine diagnostic… read more here.
Keywords: translocation; burkitt lymphoma; lymphoma interpreting; myc gene ... See more keywords
Radiosensitizing Effect of Celastrol by Inhibiting G2/M Phase Arrest Induced by the c-myc Gene of Human SW1353 Chondrosarcoma Cells: Network and Experimental Analyses
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/1948657
Abstract: Objective Studies have unveiled that the components of Tripterygium wilfordii Hook F (TWHF) such as celastrol could attenuate apoptosis and proliferation of various tumor cells. This study is focused on the radiosensitization effect and apoptotic… read more here.
Keywords: effect; myc gene; celastrol; gene ... See more keywords
The Prognostic Impact of MYC Gene-Related Abnormalities on Multiple Myeloma Outcome through Fluorescence in situ Hybridization Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Acta Haematologica"
DOI: 10.1159/000521902
Abstract: Introduction: Chromosomal abnormalities (CAs) have been identified as important factors in determining the biological features and prognostic value of multiple myeloma (MM). MYC gene-related abnormalities (MYC GAs) are one of the CAs, but their unfavorable… read more here.
Keywords: gas; impact; myc gas; myc gene ... See more keywords
Correlation of MYC gene signature variations with clinical response to fimepinostat in patients with aggressive B-cell lymphoma.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e15654
Abstract: e15654Background: Fimepinostat (F), a small molecule dual inhibitor of PI3K α, β, and δ isoforms and Class I and II histone deacetylases (HDACs), is currently under investigation for the treatment ... read more here.
Keywords: variations clinical; correlation myc; myc gene; signature variations ... See more keywords
Radiosensitizing effects of c-myc gene knockdown-induced G2/M phase arrest by intrinsic stimuli via the mitochondrial signaling pathway
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DOI: 10.3892/or.2020.7806
Abstract: Osteosarcoma is the most common primary malignant bone tumor in children and adolescents and its long-term survival rate has stagnated in the past decades. Previous studies have shown that tumors in the G2/M phase are… read more here.
Keywords: phase arrest; gene; radiosensitizing effects; myc gene ... See more keywords