Combined Targeting of Distinct c-Myc and JunB Transcriptional Programs for Multiple Myelioma Therapy
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DOI: 10.1182/blood-2019-125202
Abstract: c-Myc plays a pivotal role in multiple myeloma (MM) pathogenesis; and the BET protein BRD4 is a key regulator of c-Myc transcription. Recently, a pathophysiologic role in MM has also been attributed to the AP-1… read more here.
Keywords: transcriptional programs; protein levels; myc junb; junb ... See more keywords