Myeloid neoplasms with MYC-positive double minutes: towards recognition as a distinct entity
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DOI: 10.1038/s41408-025-01244-6
Abstract: (dmin) is a rare cytogenetic phenomenon, predominantly associated with acute myeloid leukemia (AML). The acentric chromosomal structures usually represent oncogene ampli fi cation, such as the MYC gene (Fig. 1A), highlighting a pivotal aspect of… read more here.
Keywords: myc positive; dmin; myc; myc dmin ... See more keywords
Paics Inhibition Is a Potential Therapeutic Strategy for MYC-Positive DLBCL
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DOI: 10.1182/blood-2019-129613
Abstract: Diffuse large B-cell lymphoma (DLBCL) is among the most common hematological malignancies with varying prognosis. As many as forty percent of patients eventually experience relapsed/refractory disease after combinatorial chemo-immunotherapies, R-CHOP, and prognosis after relapse is… read more here.
Keywords: dlbcl; positive dlbcl; myc positive; myc ... See more keywords