SAFETY AND EFFICACY OF THE “CARMEN” REGIMEN, A NEW DOSE‐DENSE SHORT‐TERM THERAPY IN PATIENTS WITH AGGRESSIVE B‐CELL LYMPHOMA AND MYC REARRANGEMENT
Sign Up to like & getrecommendations! Published in 2021 at "Hematological Oncology"
DOI: 10.1002/hon.93_2880
Abstract: Introduction: Patients (pts) with aggressive B-cell lymphoma and MYC rearrangement exhibits poor outcome after R-CHOP treatment. In the last decade, these pts were treated with a new dose-dense, short-term therapy termed “CARMEN”, at several Italian… read more here.
Keywords: hgbcl pts; myc rearrangement; consolidation; induction ... See more keywords
High incidence of MYC rearrangement in human immunodeficiency virus‐positive plasmablastic lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Histopathology"
DOI: 10.1111/his.13959
Abstract: MYC rearrangements are the main cytogenetic alterations in plasmablastic lymphoma (PBL). We aimed to investigate the relationship between MYC rearrangement and the clinicopathological features of PBL. read more here.
Keywords: high incidence; myc rearrangement; plasmablastic lymphoma;
Management of Primary Gastrointestinal Non-Hodgkin Lymphoma with Lenalidomide
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-122159
Abstract: Primary gastrointestinal non-Hodgkin lymphoma is a heterogeneous malignancy with limited data to guide management. We analyzed the clinical characteristics and treatment outcomes of patients with primary gastrointestinal non-Hodgkin lymphoma treated with or without lenalidomide in… read more here.
Keywords: gastrointestinal non; lymphoma; myc rearrangement; analysis ... See more keywords
Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14393
Abstract: Despite improved clinical outcomes of diffuse large B-cell lymphoma, a certain proportion of patients still develop a primary refractory disease. To overcome these lymphomas that are intractable to existing treatment strategies, the tumor microenvironment has… read more here.
Keywords: lymphoma; myc rearrangement; emetine; lymphoma cells ... See more keywords
MYC Immunohistochemistry Predicts MYC Rearrangements by FISH
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2017.00209
Abstract: MYC is the proto-oncogene classically associated with Burkitt lymphoma (BL) located at chromosomal locus 8q24. Rearrangements of MYC are seen in nearly 100% of BL but have been reported in 3–16% of diffuse large B-cell… read more here.
Keywords: myc rearrangement; myc rearrangements; rearrangements fish; cell ... See more keywords