Tumour necrosis as assessed with 18F-FDG PET is a potential prognostic marker in diffuse large B cell lymphoma independent of MYC rearrangements
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DOI: 10.1007/s00330-019-06178-9
Abstract: ObjectivesMYC gene rearrangements in diffuse large B cell lymphomas (DLBCLs) result in high proliferation rates and are associated with a poor prognosis. Strong proliferation is associated with high metabolic demand and tumour necrosis. The aim… read more here.
Keywords: necrosis; analysis; fdg pet; myc rearrangements ... See more keywords
High-resolution architecture and partner genes of MYC rearrangements in lymphoma with DLBCL morphology.
Sign Up to like & getrecommendations! Published in 2018 at "Blood advances"
DOI: 10.1182/bloodadvances.2018023572
Abstract: Genomic rearrangements in the MYC locus occur in ∼12% of lymphomas with diffuse large B-cell lymphoma (DLBCL) morphology and are associated with inferior outcome. Previous studies exploring MYC rearrangements have primarily used fluorescence in situ… read more here.
Keywords: lymphoma dlbcl; partner; dlbcl morphology; myc rearrangements ... See more keywords
MYC Immunohistochemistry Predicts MYC Rearrangements by FISH
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DOI: 10.3389/fonc.2017.00209
Abstract: MYC is the proto-oncogene classically associated with Burkitt lymphoma (BL) located at chromosomal locus 8q24. Rearrangements of MYC are seen in nearly 100% of BL but have been reported in 3–16% of diffuse large B-cell… read more here.
Keywords: myc rearrangement; myc rearrangements; rearrangements fish; cell ... See more keywords