HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1
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DOI: 10.3390/cancers11101436
Abstract: Therapy of acute myeloid leukemia (AML) is unsatisfactory. Histone deacetylase inhibitors (HDACi) are active against leukemic cells in vitro and in vivo. Clinical data suggest further testing of such epigenetic drugs and to identify mechanisms… read more here.
Keywords: catenin myc; wt1; myc wt1; hdac3 ... See more keywords