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Published in 2022 at "Cancer medicine"
DOI: 10.1002/cam4.4583
Abstract: BACKGROUND This study aimed to better understand the prognostic effect of multiple genetic markers and identify more subpopulations at ultra high risk of poor outcome in bone marrow (BM) metastatic neuroblastoma (NB). METHODS We screened…
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Keywords:
ultra high;
amplification;
mycn amplification;
high risk ... See more keywords
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Published in 2020 at "European Radiology"
DOI: 10.1007/s00330-020-07246-1
Abstract: To construct a CT-based radiomics signature and assess its performance in predicting MYCN amplification (MNA) in pediatric patients with neuroblastoma. Seventy-eight pediatric patients with neuroblastoma were recruited (55 in training cohort and 23 in test…
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Keywords:
radiomics signature;
clinical factors;
based radiomics;
mycn amplification ... See more keywords
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Published in 2021 at "Ophthalmic Genetics"
DOI: 10.1080/13816810.2021.1923038
Abstract: ABSTRACT Background: Retinoblastoma (Rb) is a childhood tumor of the developing retina where predisposition is caused by RB1 pathogenic variants. MYCN amplification (MYCNA ) has been implicated in around 2% of sporadic unilateral Rb tumors…
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Keywords:
pathogenic variants;
multiple ligation;
mycn amplification;
rb1 pathogenic ... See more keywords
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Published in 2019 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlz064
Abstract: Adult spinal cord ependymomas are typically low grade and have a relatively favorable clinical course following gross total resection. We report 4 cases of anaplastic spinal cord ependymoma with MYCN amplification, an exceptionally rare finding.…
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Keywords:
mycn amplification;
cord;
cord ependymomas;
spinal cord ... See more keywords
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Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.929123
Abstract: Neuroblastoma is the most common extracranial solid tumor found in children and despite intense multi-modal therapeutic approaches, low overall survival rates of high-risk patients persist. Tumors with heterozygous loss of chromosome 11q and MYCN amplification…
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Keywords:
chromosome 11q;
checkpoint kinase;
loss;
11q loss ... See more keywords
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Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1134772
Abstract: Introduction Patients with stage 3 neuroblastoma (NBL) according to International Neuroblastoma Staging System (INSS) without MYCN amplification represent a heterogenous group with respect to disease presentation and prognosis. Methods Retrospective analysis of 40 stage 3…
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Keywords:
children months;
chromosomal aberrations;
mycn amplification;
pathology ... See more keywords