A novel mutation in MYCN gene causing congenital absence of the flexor pollicis longus tendon as an unusual presentation of Feingold syndrome 1.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Dysmorphology"
DOI: 10.1097/mcd.0000000000000342
Abstract: Feingold syndrome 1 (FGLDS1) is an autosomal dominant malformation syndrome, characterized by skeletal anomalies, microcephaly, facial dysmorphism, gastrointestinal atresias and learning disabilities. Mutations in the MYCN gene are known to be the cause of this… read more here.
Keywords: absence flexor; congenital absence; mycn gene; feingold syndrome ... See more keywords
Prediction of MYCN Gene Amplification in Pediatric Neuroblastomas: Development of a Deep Learning-Based Tool for Automatic Tumor Segmentation and Comparative Analysis of Computed Tomography-Based Radiomics Features Harmonization.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of computer assisted tomography"
DOI: 10.1097/rct.0000000000001480
Abstract: OBJECTIVE MYCN oncogene amplification is closely linked to high-grade neuroblastoma with poor prognosis. Accurate quantification is essential for risk assessment, which guides clinical decision making and disease management. This study proposes an end-to-end deep-learning framework… read more here.
Keywords: mycn gene; tumor segmentation; amplification; tumor ... See more keywords
Neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene or MYCN gene
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Pathology"
DOI: 10.1136/jcp-2022-208476
Abstract: The MYCN gene belongs to the MYC family of transcription factors. Amplification of MYCN, first discovered in neuroblastoma cells, ushered in the era of cancer genomics. The MYCN gene and MYCN protein are extensively studied… read more here.
Keywords: mycn gene; myc avian; mycn; derived myc ... See more keywords