An immunomodulatory role for the Mycobacterium tuberculosis Acr protein in the formation of the tuberculous granuloma
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13998
Abstract: The tuberculous granuloma is a compact aggregate of dormant bacteria encapsulated by host macrophages. It is commonly regarded as a product of the host defense designed to isolate infectious mycobacteria. This work demonstrates that exposure… read more here.
Keywords: protein; mycobacterium; tuberculous granuloma; immunomodulatory role ... See more keywords
A Simple Glycolipid Mimic of the Phosphatidylinositol Mannoside Core from Mycobacterium tuberculosis Inhibits Macrophage Cytokine Production
Sign Up to like & getrecommendations! Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201800150
Abstract: Glycolipids from Mycobacterium tuberculosis have a profound impact on the innate immune response of the host. Macrophage‐inducible C‐type lectin (Mincle) is a pattern‐recognition receptor that has been shown to bind trehalose dimycolate (TDM) from the… read more here.
Keywords: mannoside; mycobacterium; mycobacterium tuberculosis; cytokine production ... See more keywords
Colony‐stimulating factor‐1‐ and interleukin‐34‐derived macrophages differ in their susceptibility to Mycobacterium marinum
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.1a0919-147r
Abstract: Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains the leading global cause of death from an infectious agent. Mycobacteria thrive within their host Mϕs and presently, there is no animal model that permits… read more here.
Keywords: susceptibility; mycobacterium marinum; csf; host ... See more keywords
Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors
Sign Up to like & getrecommendations! Published in 2020 at "ChemistryOpen"
DOI: 10.1002/open.202000042
Abstract: Abstract Non‐tuberculous mycobacterium (NTM) infections, such as those caused by Mycobacterium abscessus, are increasing globally. Due to their intrinsic drug resistance, M. abscessus pulmonary infections are often difficult to cure using standard chemotherapy. We previously… read more here.
Keywords: mycobacterium; piperidinol; abscessus; structure based ... See more keywords
Identification of putative microRNAs in the complete genome of Mycobacterium avium and their possible interaction with human transcripts.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of applied genetics"
DOI: 10.1007/s13353-021-00666-9
Abstract: The grievous adversity regarding Mycobacterium avium is its ubiquitous nature. Isolation of the bacteria from drinking water, house dust, and soil, etc., is an alarming issue for the scientific community. The microRNAs are the molecular… read more here.
Keywords: mature; mycobacterium; genome mycobacterium; complete genome ... See more keywords
Mycobacterium Wolinskyi: A New Non-Tuberculous Mycobacterium Associated with Cardiovascular Infections?
Sign Up to like & getrecommendations! Published in 2021 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-021-00416-8
Abstract: Mycobacterium wolinskyi is a rapid-growth non-tuberculous mycobacterium. Twenty-one cases of M. wolinskyi infection have been described so far, more than half as cardiovascular or postoperative cardiothoracic infections. We report the case of a patient with… read more here.
Keywords: new non; tuberculous mycobacterium; mycobacterium; wolinskyi new ... See more keywords
Mycobacteriophage SWU1-Functionalized magnetic particles for facile bioluminescent detection of Mycobacterium smegmatis.
Sign Up to like & getrecommendations! Published in 2021 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2020.12.009
Abstract: Mycobacterium tuberculosis (M. tuberculosis), the causative agent of tuberculosis, ranks one of the most dangerous pathogens for its large deaths toll. Due to its characteristic extremely slow growth, the conventional culture-based protocol cannot meet the requirement… read more here.
Keywords: mycobacterium; smegmatis; mycobacteriophage swu1; tuberculosis ... See more keywords
Diagnostic investigation for the detection of mycobacteria in samples of fish feeds and tissue from sea bream and sea bass with severe granulomatous lesions
Sign Up to like & getrecommendations! Published in 2022 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.737283
Abstract: Abstract We report on a case of a sea bass and sea bream aquaculture farm in Greece, with many incidents of severe dermal and visceral granulomatous lesions detected during routine inspection and post-mortem examination. The… read more here.
Keywords: fish feeds; histopathology; tissue; sea bass ... See more keywords
MksB, an alternate condensin from Mycobacterium smegmatis is involved in DNA binding and condensation.
Sign Up to like & getrecommendations! Published in 2020 at "Biochimie"
DOI: 10.1016/j.biochi.2020.03.002
Abstract: The structural maintenance of chromosomes (SMC) proteins play a vital role in genome stability and chromosome organization in all domains of life. Previous reports show that smc deletion causes decondensation of chromosome and an increased… read more here.
Keywords: mycobacterium; dna; condensation; dna binding ... See more keywords
Complete genome sequence of a phthalic acid esters degrading Mycobacterium sp. YC-RL4
Sign Up to like & getrecommendations! Published in 2017 at "Brazilian Journal of Microbiology"
DOI: 10.1016/j.bjm.2016.09.022
Abstract: Mycobacterium sp. YC-RL4 is capable of utilizing a broad range of phthalic acid esters (PAEs) as sole source of carbon and energy for growth. The preliminary studies demonstrated its high degrading efficiency and good performance… read more here.
Keywords: acid esters; mycobacterium; phthalic acid; complete genome ... See more keywords
A re-investigation of the mycolic acids of Mycobacterium avium.
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2020.104928
Abstract: Mycolic acid methyl esters were extracted from Mycobacterium avium by a mild saponification protocol, designed to preserve labile components. The resulting mixture of α-, keto- and wax ester mycolates was accompanied by some degraded ω-carboxymycolic… read more here.
Keywords: mycobacterium; wax ester; ester mycolates; mycobacterium avium ... See more keywords