Transposon mutagenesis in Mycobacterium kansasii links a small RNA gene to colony morphology and biofilm formation and identifies 9,885 intragenic insertions that do not compromise colony outgrowth
Sign Up to like & getrecommendations! Published in 2020 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.988
Abstract: Mycobacterium kansasii (Mk) is a resilient opportunistic human pathogen that causes tuberculosis‐like chronic pulmonary disease and mortality stemming from comorbidities and treatment failure. The standard treatment of Mk infections requires costly, long‐term, multidrug courses with… read more here.
Keywords: small rna; colony; transposon mutagenesis; mycobacterium kansasii ... See more keywords
Osteomyelitis due to Mycobacterium kansasii in a patient with sarcoidosis
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DOI: 10.1016/j.idcr.2017.04.001
Abstract: A 45-year-old male presented with severe pain in his left foot. His medical history included stage IV biopsy-proven pulmonary sarcoidosis diagnosed six years earlier, with negative acid-fast stain in lymph node biopsy and bronchoalveolar lavage… read more here.
Keywords: treatment; kansasii; sarcoidosis; mycobacterium kansasii ... See more keywords
Necrotizing pneumonia in a patient with untreated Mycobacterium kansasii infection
Sign Up to like & getrecommendations! Published in 2019 at "Respiratory Medicine Case Reports"
DOI: 10.1016/j.rmcr.2019.100849
Abstract: Mycobacterium kansasii is the second most commonly occurring Non-Tuberculous Mycobacteria (NTM) in the United States. Infection is typically seen in middle aged males, and the risk of infection is greatly increased in immunocompromised hosts. Pulmonary… read more here.
Keywords: kansasii infection; necrotizing pneumonia; infection; patient untreated ... See more keywords
Spontaneous resolution of Mycobacterium kansasii presenting as a spiculated lung mass
Sign Up to like & getrecommendations! Published in 2021 at "Respiratory Medicine Case Reports"
DOI: 10.1016/j.rmcr.2021.101512
Abstract: A 68-year old woman with a long smoking history underwent lung cancer screening by low-dose computed tomography. This detected a 3.0 cm spiculated mass in the left upper lobe. Transbronchial biopsy revealed necrotizing granulomatous inflammation… read more here.
Keywords: resolution; mass; mycobacterium kansasii; kansasii presenting ... See more keywords
Molecular typing of Mycobacterium kansasii using pulsed-field gel electrophoresis and a newly designed variable-number tandem repeat analysis
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21562-z
Abstract: Molecular epidemiological studies of Mycobacterium kansasii are hampered by the lack of highly-discriminatory genotyping modalities. The purpose of this study was to design a new, high-resolution fingerprinting method for M. kansasii. Complete genome sequence of… read more here.
Keywords: tandem repeat; kansasii; variable number; mycobacterium kansasii ... See more keywords
Huge cutaneous abscess and severe symptomatic hypercalcaemia secondary to Mycobacterium kansasii infection in an immunocompetent patient
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-241662
Abstract: Mycobacterium kansasii is among the most common non-tuberculous mycobacteria causing human infections. Apart from pulmonary infection, the most common infection caused by M. kansasii is skin and soft tissue infection, and it is very rare… read more here.
Keywords: infection; cutaneous abscess; huge cutaneous; mycobacterium kansasii ... See more keywords
Non-tuberculous mycobacterial thoracic osteomyelitis in an immunocompetent host: a rare presentation of Mycobacterium kansasii
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2022-249629
Abstract: An immunocompetent man in his 40s presented with 3 months of mid-thoracic back pain which progressed to include progressive paraesthesias and lower extremity weakness. Investigations revealed thoracic spine osteomyelitis with signs of cord compression. He underwent… read more here.
Keywords: osteomyelitis; thoracic; mycobacterium; mycobacterium kansasii ... See more keywords
Disseminated mycobacteriosis caused by Mycobacterium kansasii in a pot-bellied pig
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Veterinary Diagnostic Investigation"
DOI: 10.1177/1040638718780189
Abstract: A 1.5-y-old spayed female Juliana pot-bellied pig was presented to the Purdue University Veterinary Teaching Hospital with a history of wasting and anorexia. Enlarged and partially mineralized lymph nodes were identified on radiographs and computed… read more here.
Keywords: bellied pig; pot bellied; mycobacterium kansasii; mycobacteriosis caused ... See more keywords
Disseminated Mycobacterium kansasii infection in a white-tailed deer and implications for public and livestock health
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Veterinary Diagnostic Investigation"
DOI: 10.1177/1040638719895475
Abstract: We document a case of Mycobacterium kansasii, a rare, zoonotic bacterium, in a white-tailed deer (WTD; Odocoileus virginianus) in East Baton Rouge Parish, Louisiana. Grossly, the deer had fibrinous pleuropneumonia with yellow, mineralized nodules scattered… read more here.
Keywords: white tailed; tailed deer; infection; kansasii ... See more keywords
Determination of Clinical Characteristics of Mycobacterium kansasii-Derived Species by Reanalysis of Isolates Formerly Reported as M. kansasii
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Laboratory Medicine"
DOI: 10.3343/alm.2021.41.5.463
Abstract: Background Seven genotypic subtypes of Mycobacterium kansasii were recently demonstrated to represent distinct species based on phylogenomic analysis. Mycobacterium kansasii sensu stricto (formerly known as subtype 1) is most frequently associated with human diseases; only… read more here.
Keywords: clinical characteristics; patients subtype; subtype kansasii; mycobacterium kansasii ... See more keywords
Repurposing β-Lactams for the Treatment of Mycobacterium kansasii Infections: An In Vitro Study
Sign Up to like & getrecommendations! Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12020335
Abstract: Mycobacterium kansasii (Mkn) causes tuberculosis-like lung infection in both immunocompetent and immunocompromised patients. Current standard therapy against Mkn infection is lengthy and difficult to adhere to. Although β-lactams are the most important class of antibiotics,… read more here.
Keywords: treatment; mkn; mycobacterium kansasii; study ... See more keywords