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   Articles with "mycobacterium smegmatis" as a keyword



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Inducible knockdown of Mycobacterium smegmatis MSMEG_2975 (glyoxalase II) affected bacterial growth, antibiotic susceptibility, biofilm, and transcriptome

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recommendations! Published in 2021 at "Archives of Microbiology"

DOI: 10.1007/s00203-021-02652-5

Abstract: Tuberculosis (TB) causes millions of deaths each year across the globe. Multiple drug-resistant (MDR) and extensively drug-resistant (XDR) mycobacterial strains have made the treatment extremely difficult. To overcome this hurdle, the development of new drug… read more here.

Keywords: inducible knockdown; mycobacterium smegmatis; glyoxalase; msmeg 2975 ... See more keywords
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Structural characterization and Kemp eliminase activity of the Mycobacterium smegmatis Ketosteroid Isomerase.

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recommendations! Published in 2021 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2021.05.007

Abstract: The Kemp elimination reaction, involving the ring-opening of benzoxazole and its derivatives under the action of natural enzymes or chemical catalysts, has been of interest to researchers since its discovery. Because this reaction does not… read more here.

Keywords: structural characterization; ketosteroid isomerase; kemp elimination; mycobacterium smegmatis ... See more keywords
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Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis.

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recommendations! Published in 2017 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2016.12.060

Abstract: Diaryltriazene derivatives were synthesized and evaluated for their antimicrobial properties. Initial experiments showed some of these compounds to have activity against both methicillin-resistant strains of Staphylococus aureus (MRSA) and Mycobacterium smegmatis, with MICs of 0.02… read more here.

Keywords: aureus mrsa; methicillin resistant; mrsa; mrsa mycobacterium ... See more keywords
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Glucosamine/L-lactide copolymers as potential carriers for the development of a sustained rifampicin release system using Mycobacterium smegmatis as a tuberculosis model

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recommendations! Published in 2019 at "Heliyon"

DOI: 10.1016/j.heliyon.2019.e01539

Abstract: The present study aims at developing a new, ultrafine particle-based efficient antibiotic delivery system for the treatment of tuberculosis. The carrier material to make the rifampicin (RIF)-loaded particles is a low molecular weight star-shaped polymer… read more here.

Keywords: system; glun lla; drug; release ... See more keywords
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Mycobacterium smegmatis bacteremia in an immunocompetent host

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recommendations! Published in 2019 at "IDCases"

DOI: 10.1016/j.idcr.2019.e00523

Abstract: Non-tuberculous mycobacteria can cause catheter associated blood stream infections. The causative agents are generally rapid growers that belong to the Mycobacterium fortuitum and Mycobacterium mucogenicum groups. A 65 year hospitalized patient with temporary central venous… read more here.

Keywords: smegmatis bacteremia; bacteremia immunocompetent; mycobacterium; mycobacterium smegmatis ... See more keywords
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Misidentification of Mycobacterium smegmatis as Mycobacterium fortuitum by DNA line probe assay

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recommendations! Published in 2021 at "Journal of Clinical Tuberculosis and Other Mycobacterial Diseases"

DOI: 10.1016/j.jctube.2021.100268

Abstract: Optimal management of infection with mycobacterial species requires accurate identification down to complex/species level due to variations in outcomes. Over the last few decades, there have been significant advances in laboratory diagnostics with development of… read more here.

Keywords: mycobacterium; mycobacterium fortuitum; line probe; dna line ... See more keywords
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PtIV- or MoVI-substituted decavanadates inhibit the growth of Mycobacterium smegmatis.

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recommendations! Published in 2021 at "Journal of inorganic biochemistry"

DOI: 10.1016/j.jinorgbio.2021.111356

Abstract: Inhibitory effects of two monosubstituted decavanadates by PtIV in monoplatino(IV)nonavanadate(V) ([H2PtIVV9O28]5-, V9Pt), and by MoIV in monomolybdo(VI)nonavanadate(V) ([MoVIV9O28]5-,V9Mo) were investigated against the growth of Mycobacterium smegmatis with the EC50 values of 0.0048 mM and 0.015 mM, respectively.… read more here.

Keywords: inhibitory effects; growth; growth mycobacterium; mycobacterium smegmatis ... See more keywords
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Features of the biochemistry of Mycobacterium smegmatis, as a possible model for Mycobacterium tuberculosis.

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recommendations! Published in 2020 at "Journal of infection and public health"

DOI: 10.1016/j.jiph.2020.06.023

Abstract: An alternate host for mycobacteria is Mycobacterium smegmatis which is used frequently. It is a directly budding eco-friendly organism not emulated as human infection. It is mainly useful for the investigation of various microorganisms in… read more here.

Keywords: biochemistry; mycobacterium; mycobacterium tuberculosis; mycobacterium smegmatis ... See more keywords
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Dynamic mathematical model development and validation of in vitro Mycobacterium smegmatis growth under nutrient- and pH-stress.

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recommendations! Published in 2021 at "Journal of theoretical biology"

DOI: 10.1016/j.jtbi.2021.110921

Abstract: Mycobacterium tuberculosis can exist within a host for lengthy periods, tolerating even antibiotic challenge. This non-heritable, antibiotic tolerant "persister" state, is thought to underlie latent Tuberculosis (TB) infection and a deeper understanding thereof could inform… read more here.

Keywords: mycobacterium; validation; dynamic mathematical; model ... See more keywords
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Rec A disruption unveils cross talk between DNA repair and membrane damage, efflux pump activity, biofilm formation in Mycobacterium smegmatis.

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recommendations! Published in 2020 at "Microbial pathogenesis"

DOI: 10.1016/j.micpath.2020.104262

Abstract: Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) has emerged in recent decades as one of the leading causes of mortality worldwide. The burden of TB is alarmingly high, with one third affected global population as… read more here.

Keywords: disruption; efflux pump; biofilm formation; pump activity ... See more keywords
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The bifunctional protein GlmU is a key factor in biofilm formation induced by alkylating stress in Mycobacterium smegmatis.

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recommendations! Published in 2019 at "Research in microbiology"

DOI: 10.1016/j.resmic.2019.03.002

Abstract: Living organisms have developed specific defence mechanisms to counteract hostile environmental conditions. Alkylation stress response mechanisms also occur in Mycobacterium tuberculosis (MTB) the pathogen responsible for tuberculosis. The effect of alkylating agents on the cellular… read more here.

Keywords: glmu; biofilm formation; stress; smegmatis ... See more keywords