Modular Synthesis and Antimicrobial Investigation of Mycoleptodiscin A and Simplified Indolosesquiterpenoids.
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DOI: 10.1021/acs.orglett.4c01932
Abstract: The structure-activity relationship of the unusual indolosesquiterpenoid mycoleptodiscin A is unknown due to natural scarcity and inefficient synthesis. A modular approach leveraging Larock indole synthesis has been established to access mycoleptodiscin A and a divergent… read more here.
Keywords: antimicrobial investigation; mycoleptodiscin; synthesis; synthesis antimicrobial ... See more keywords