The role of corynomycolic acids in Corynebacterium-host interaction
Sign Up to like & getrecommendations! Published in 2018 at "Antonie van Leeuwenhoek"
DOI: 10.1007/s10482-018-1036-6
Abstract: Within the Actinobacteria, the genera Corynebacterium, Mycobacterium, Nocardia and Rhodococcus form the so-called CMNR group, also designated as mycolic acid-containing actinomycetes. Almost all members of this group are characterized by a mycolic acid layer, the… read more here.
Keywords: corynomycolic acids; mycolic acid; role corynomycolic; corynebacterium ... See more keywords
Role of long-chain acyl-CoAs in the regulation of mycolic acid biosynthesis in mycobacteria
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DOI: 10.1098/rsob.170087
Abstract: One of the dominant features of the biology of Mycobacterium tuberculosis, and other mycobacteria, is the mycobacterial cell envelope with its exceptional complex composition. Mycolic acids are major and very specific components of the cell… read more here.
Keywords: biosynthesis; mycolic acid; mabr; acyl coas ... See more keywords
Cg1246, a new player in mycolic acid biosynthesis in Corynebacterium glutamicum.
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology"
DOI: 10.1099/mic.0.001171
Abstract: Mycolic acids are key components of the complex cell envelope of Corynebacteriales. These fatty acids, conjugated to trehalose or to arabinogalactan form the backbone of the mycomembrane. While mycolic acids are essential to the survival… read more here.
Keywords: corynebacterium glutamicum; cg1246; mycolic acid; acid biosynthesis ... See more keywords
PatA Regulates Isoniazid Resistance by Mediating Mycolic Acid Synthesis and Controls Biofilm Formation by Affecting Lipid Synthesis in Mycobacteria
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DOI: 10.1128/spectrum.00928-23
Abstract: Tuberculosis, caused by Mycobacterium tuberculosis, leads to a large number of human deaths every year. This is so serious, which is due mainly to the drug resistance of mycobacteria. ABSTRACT Lipids are prominent components of… read more here.
Keywords: acid synthesis; biofilm formation; mycolic acid; synthesis ... See more keywords
Evaluation of a novel ELISA test using synthetic mycolic acid antigens for serodiagnosis of non-tuberculous mycobacterial (NTM) infections
Sign Up to like & getrecommendations! Published in 2023 at "Thorax"
DOI: 10.1136/thorax-2022-218800
Abstract: The diagnosis of non-tuberculous mycobacteria (NTM) is a particular challenge in people with cystic fibrosis. Current standard diagnostic approaches rely on serial sputum culture, which is resource demanding, dependent on patient expectoration and may be… read more here.
Keywords: infection; mycolic acid; non tuberculous; acid antigens ... See more keywords
Identifying the Novel Inhibitors Against the Mycolic Acid Biosynthesis Pathway Target “mtFabH” of Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.818714
Abstract: Mycolic acids are the key constituents of mycobacterial cell wall, which protect the bacteria from antibiotic susceptibility, helping to subvert and escape from the host immune system. Thus, the enzymes involved in regulating and biosynthesis… read more here.
Keywords: mycobacterium tuberculosis; biosynthesis; lead molecules; mycolic acid ... See more keywords
The role of APTX4870 peptide in reducing cellular inflammatory responses by inhibiting Mycobacterium tuberculosis-derived mycolic acid-induced cytotoxicity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.993897
Abstract: Tuberculosis is a serious zoonotic disease caused by Mycobacterium tuberculosis (M.tb) and the M.tb complex. Mycolic acid is an extracellular carbohydrate polymer produced, secreted, and accumulated outside the cells of various Mycobacterium tuberculosis strains. Mycolic… read more here.
Keywords: mycobacterium tuberculosis; acid; acid induced; mycolic acid ... See more keywords