Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202590
Abstract: Diabetes manifests as chronic inflammation and leads to the development diabetic cardiomyopathy (DCM). Targeting key proteins in inflammatory signaling may provide new therapy for DCM. In this study, the authors explore the pharmacological effects and… read more here.
Keywords: inflammation; myd88; myd88 dependent; diabetic cardiomyopathy ... See more keywords
Molecular characterization of Pacific oyster (Crassostrea gigas) IRAK4 gene and its role in MyD88‐dependent pathway
Sign Up to like & getrecommendations! Published in 2017 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.02.004
Abstract: Abstract Interleukin‐1 receptor‐associated kinases (IRAKs) play important roles in MyD88‐dependent TLR signaling, the crucial innate immune pathway in molluscs. In this study, we examined the full‐length IRAK4 genetic sequence in the Pacific oyster (Crassostrea gigas)… read more here.
Keywords: oyster crassostrea; pacific oyster; crassostrea gigas; tlr ... See more keywords
Anti-inflammatory action of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) suppresses both the MyD88-dependent and TRIF-dependent pathways of TLR4 signaling in LPS-stimulated RAW264.7 cells.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2017.04.029
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE The roots of Rubia cordifolia L. have been widely used as a traditional herbal medicine in Northeast Asia for treating inflammatory diseases. AIM OF THE STUDY To elucidate the anti-inflammatory mechanism of 2-carbomethoxy-2,3-epoxy-3-… read more here.
Keywords: anti inflammatory; lps; cmep; myd88 dependent ... See more keywords
Acanthamoeba Activates Macrophages Predominantly through Toll-Like Receptor 4- and MyD88-Dependent Mechanisms To Induce Interleukin-12 (IL-12) and IL-6
Sign Up to like & getrecommendations! Published in 2017 at "Infection and Immunity"
DOI: 10.1128/iai.01054-16
Abstract: ABSTRACT Acanthamoeba castellanii is a ubiquitous free-living amoeba with a worldwide distribution that can occasionally infect humans, causing particularly severe infections in immunocompromised individuals. Dissecting the immunology of Acanthamoeba infections has been considered problematic due… read more here.
Keywords: toll like; acanthamoeba activates; like receptor; acanthamoeba ... See more keywords
Effects of Sparassis latifolia neutral polysaccharide on immune activity via TLR4-mediated MyD88-dependent and independent signaling pathways in RAW264.7 macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.994971
Abstract: Background Sparassis latifolia (S. latifolia) is a precious edible fungus with multiple biological activities. To date, no study has been investigated the underlying molecular mechanism of immunoregulation caused by the neutral polysaccharide of S. latifolia.… read more here.
Keywords: neutral polysaccharide; raw264; latifolia neutral; sparassis latifolia ... See more keywords
IL-1/MyD88-Dependent G-CSF and IL-6 Secretion Mediates Postburn Anemia.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of immunology"
DOI: 10.4049/jimmunol.2200785
Abstract: The anemia of critical illness (ACI) is a nearly universal pathophysiological consequence of burn injury and a primary reason burn patients require massive quantities of transfused blood. Inflammatory processes are expected to drive postburn ACI… read more here.
Keywords: csf secretion; postburn aci; csf; secretion ... See more keywords
Role of the MyD88 Dependent Pathway in Degenerative Disc Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Turkish neurosurgery"
DOI: 10.5137/1019-5149.jtn.42017-22.2
Abstract: AIM We aim to define the substantial role of the TLR4 signaling pathway in the MyD88-dependent pathway and evaluate the results of TLR4 activation in nucleus pulposus cells. Moreover, we aim to associate this pathway… read more here.
Keywords: degeneration; role; myd88 dependent; dependent pathway ... See more keywords