Articles with "myd88 mutant" as a keyword



Targeting MYD88-Mutant DLBCL with IRAKIMiDs: A Comparison to IRAK4 Kinase Inhibition and Evaluation of Synergy with Rational Combinations

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Published in 2020 at "Blood"

DOI: 10.1182/blood-2020-135898

Abstract: Introduction: MYD88 mutations are found in 25% of DLBCL and are associated with an inferior survival. MYD88 is an adapter molecule, forming the core of the Myddosome complex. MYD88 mutations constitutively activate pathways such as… read more here.

Keywords: equity holder; current equity; therapeutics current; myd88 ... See more keywords