Correlations of quantitative MRI metrics with myelin basic protein (MBP) staining in a murine model of demyelination
Sign Up to like & getrecommendations! Published in 2019 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4116
Abstract: Myelin imaging in the central nervous system is essential for monitoring pathologies involving white matter alterations. Various quantitative MRI protocols relying on the modeling of the interactions of water protons with myelinated tissues have shown… read more here.
Keywords: demyelination; myelin basic; model; basic protein ... See more keywords
Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding to independent l-lysine-containing domains.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.06.131
Abstract: Myelin basic protein (MBP) is a key component of myelin, the specialized lipid membrane that encases the axons of all neurons. Both plasminogen (Pg) and tissue-type plasminogen activator (t-PA) bind to MBP with high affinity.… read more here.
Keywords: myelin basic; mbp; activation; basic protein ... See more keywords
α2 isoform of Na+,K+-ATPase via Na+,Ca2+ exchanger modulates myelin basic protein synthesis in oligodendrocyte lineage cells in vitro.
Sign Up to like & getrecommendations! Published in 2018 at "Cell calcium"
DOI: 10.1016/j.ceca.2018.03.003
Abstract: Oligodendrocytes in the CNS myelinate neuronal axons, facilitating rapid propagation of action potentials. Myelin basic protein (MBP) is an essential component of myelin and its absence results in severe hypomyelination. In oligodendrocyte lineage cell (OLC)… read more here.
Keywords: synthesis; myelin basic; ca2; basic protein ... See more keywords
Reciprocal nerve staining (RNS) for the concurrent detection of choline acetyltransferase and myelin basic protein on paraffin-embedded sections
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2018.10.040
Abstract: BACKGROUND Objective of our work was to develop a sequential double nonfluorescent immunostaining method which allows the selective identification of myelinated motor fibers in paraffin-embedded samples of peripheral nerves. Motor recovery after a nerve gap-lesion… read more here.
Keywords: paraffin embedded; myelin basic; choline acetyltransferase; basic protein ... See more keywords
Identification of a novel variant of Golli myelin basic protein BG21 in the uniquely neuroprotective white-footed mouse
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.02.006
Abstract: The myelin basic protein (MBP) gene is a complex gene which codes for several distinct forms of MBP. The various forms of MBP are functionally involved in the development of the nervous system, T-cell regulation,… read more here.
Keywords: novel variant; myelin basic; footed mouse; white footed ... See more keywords
Pubertal hormones mediate sex differences in levels of myelin basic protein in the orbitofrontal cortex of adult rats
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2019.03.041
Abstract: Previous work from our lab revealed that adult female rats have increased levels of myelin basic protein (MBP), a marker for myelination, in the orbitofrontal cortex (OFC) as compared to adult males. The goal of… read more here.
Keywords: adult; myelin basic; sex; orbitofrontal cortex ... See more keywords
Transcriptional regulators of the Golli/myelin basic protein locus integrate additive and stealth activities
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1008752
Abstract: Myelin is composed of plasma membrane spirally wrapped around axons and compacted into dense sheaths by myelin-associated proteins. Myelin is elaborated by neuroepithelial derived oligodendrocytes in the central nervous system (CNS) and by neural crest… read more here.
Keywords: myelin basic; myelin; basic protein; locus ... See more keywords
Multiple Sclerosis: Enzymatic Cross Site-Specific Recognition and Hydrolysis of H3 Histone by IgGs against H3, H1, H2A, H2B, H4 Histones, Myelin Basic Protein, and DNA
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10102663
Abstract: Histones have a specific key role in the remodeling of chromatin and gene transcription. In the blood, free histones are damage-connected proteins. Myelin basic protein (MBP) is the major component of the myelin-proteolipid sheath of… read more here.
Keywords: myelin basic; dna; mbp dna; basic protein ... See more keywords
Methylmercury Causes Neurodegeneration and Downregulation of Myelin Basic Protein in the Spinal Cord of Offspring Rats after Maternal Exposure
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073777
Abstract: Methylmercury (MeHg) is one of the most dangerous toxic pollutants spread throughout the earth. Chronic MeHg intoxication by contaminated food ingestion is the most common threat to human health, including impairment to the developing fetus.… read more here.
Keywords: cord; myelin basic; maternal exposure; spinal cord ... See more keywords
Catalytic Antibodies in Bipolar Disorder: Serum IgGs Hydrolyze Myelin Basic Protein
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137397
Abstract: The pathogenesis of bipolar affective disorder is associated with immunological imbalances, a general pro-inflammatory status, neuroinflammation, and impaired white matter integrity. Myelin basic protein (MBP) is one of the major proteins in the myelin sheath… read more here.
Keywords: myelin basic; basic protein; bipolar disorder; mbp ... See more keywords