Biomechanically-adapted immunohydrogels reconstructing myelin sheath for peripheral nerve regeneration.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202201596
Abstract: Myelin sheath reconstruction plays an important role in peripheral nerve regeneration. But the hindered reconstruction of myelin sheath due to the inadequate repair phenotypes of macrophages and Schwann cells after peripheral nerve injury often causes… read more here.
Keywords: biomechanically adapted; peripheral nerve; nerve regeneration; myelin sheath ... See more keywords
Calcium control of myelin sheath growth
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DOI: 10.1038/s41593-017-0043-7
Abstract: New studies provide compelling evidence that the number and length of myelin sheaths generated by oligodendrocytes in the CNS are controlled by local calcium levels, linking axonal activity to individual myelin sheath formation. read more here.
Keywords: sheath growth; calcium control; myelin sheath; calcium ... See more keywords
Myelin sheath structure and regeneration in peripheral nerve injury repair
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1910292116
Abstract: Significance Afferent and efferent nerve fibers cannot be distinguished based on the axonal diameter or the presence of the Remark bundle. The compaction of the myelin sheath involves 2 steps: 1) The distance between the… read more here.
Keywords: sheath; myelin sheath; nerve; structure regeneration ... See more keywords
Celecoxib Exerts a Therapeutic Effect Against Demyelination by Improving the Immune and Inflammatory Microenvironments
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s282128
Abstract: Background The myelin sheath can be damaged by genetic and/or environmental factors, leading to demyelinating diseases, for which effective treatments are lacking. Recently, cyclooxygenase-2 (COX-2) overexpression was detected in demyelinating lesions both in patients and… read more here.
Keywords: therapeutic effect; myelin sheath; effect demyelination; demyelination ... See more keywords
Advanced Maternal Age Impairs Myelination in Offspring Rats
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.850213
Abstract: The effects of advanced maternal age (AMA) on the neurodevelopment of offspring are becoming increasingly important. Myelination is an important aspect of brain development; however, a limited number of studies have focused on the effects… read more here.
Keywords: myelination; myelin sheath; ama; advanced maternal ... See more keywords