Preferential conduction block of myelinated axons by nitric oxide
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.23918
Abstract: Conduction block by nitric oxide (NO) was examined in myelinated and unmyelinated axons from both the central nervous system and peripheral nervous system. In rat vagus nerves, mouse optic nerves at P12–P23, adult and developing… read more here.
Keywords: unmyelinated axons; conduction block; nitric oxide; conduction ... See more keywords
Loss of myelinated axons and astrocytosis in an autopsy case of acute encephalopathy with biphasic seizures and late reduced diffusion
Sign Up to like & getrecommendations! Published in 2018 at "Brain and Development"
DOI: 10.1016/j.braindev.2018.06.004
Abstract: Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is the most common pediatric encephalopathy in Japan, however, the exact neuropathology remains uncertain. The postmortem neuropathology in a patient with AESD revealed reduction of… read more here.
Keywords: encephalopathy biphasic; reduced diffusion; acute encephalopathy; biphasic seizures ... See more keywords
gACSON software for automated segmentation and morphology analyses of myelinated axons in 3D electron microscopy
Sign Up to like & getrecommendations! Published in 2022 at "Computer methods and programs in biomedicine"
DOI: 10.1016/j.cmpb.2022.106802
Abstract: BACKGROUND AND OBJECTIVE Advances in electron microscopy (EM) now allow three-dimensional (3D) imaging of hundreds of micrometers of tissue with nanometer-scale resolution, providing new opportunities to study the ultrastructure of the brain. In this work,… read more here.
Keywords: microscopy; myelinated axons; gacson; software ... See more keywords
The Role of Neurofilament Transport in the Radial Growth of Myelinated Axons.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular biology of the cell"
DOI: 10.1091/mbc.e22-12-0565
Abstract: The cross-sectional area of myelinated axons increases greatly during postnatal development in mammals and is an important influence on axonal conduction velocity. This radial growth is driven primarily by an accumulation of neurofilaments which are… read more here.
Keywords: growth myelinated; growth; radial growth; myelinated axons ... See more keywords
All-optical observation on activity-dependent nanoscale dynamics of myelinated axons
Sign Up to like & getrecommendations! Published in 2022 at "Neurophotonics"
DOI: 10.1117/1.nph.10.1.015003
Abstract: In the mammalian brain, rapid conduction of neural information is supported by the myelin, whose functional efficacy shows steep dependence on its nanoscale cytoarchitecture. Although previous in vitro studies suggested that neural activity accompanies nanometer-scale… read more here.
Keywords: dependent nanoscale; activity dependent; myelinated axons; activity ... See more keywords
Nodal Na+ and Ca2+ flux dynamics in cortical myelinated axons
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2025.1662730
Abstract: Functional neuronal connectivity relies on long-range propagation of action potentials by myelinated axons. This process critically depends on the distribution and biophysical properties of ion channels clustered at specialized, regularly spaced domains, the nodes of… read more here.
Keywords: myelinated axons; ca2; ca2 flux; action potential ... See more keywords
Non-Invasive High-Resolution Imaging of In Vivo Human Myelinated Axons
Sign Up to like & getrecommendations! Published in 2024 at "Diagnostics"
DOI: 10.3390/diagnostics14030253
Abstract: This work aims to reveal the microscopic (2–3 micrometer resolution) appearance of human myelinated nerve fibers in vivo for the first time. We analyzed the myelinated retinal nerve fibers of a male patient without other… read more here.
Keywords: myelinated axons; resolution; human myelinated; nerve fibers ... See more keywords