N-myc downstream regulated family member 1 (NDRG1) is enriched in myelinating oligodendrocytes and impacts myelin degradation in response to demyelination.
Sign Up to like & getrecommendations! Published in 2021 at "Glia"
DOI: 10.1002/glia.24108
Abstract: The N-myc downstream regulated gene family member 1 (NDRG1) is a gene whose mutation results in peripheral neuropathy with central manifestations. While most of previous studies characterized NDRG1 role in Schwann cells, the detection of… read more here.
Keywords: demyelination; family member; downstream regulated; myc downstream ... See more keywords
Induction of Myelinating Oligodendrocytes in Human Cortical Spheroids
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DOI: 10.1038/s41592-018-0081-4
Abstract: Cerebral organoids provide an accessible system for investigations of cellular composition, interactions, and organization but have lacked oligodendrocytes, the myelinating glia of the central nervous system. Here we reproducibly generated oligodendrocytes and myelin in ‘oligocortical… read more here.
Keywords: induction myelinating; system; human cortical; oligodendrocytes human ... See more keywords