A quantitative analysis of heterogeneities and hallmarks in acute myelogenous leukaemia
Sign Up to like & getrecommendations! Published in 2019 at "Nature biomedical engineering"
DOI: 10.1038/s41551-019-0387-2
Abstract: Acute myelogenous leukaemia (AML) is associated with risk factors that are largely unknown and with a heterogeneous response to treatment. Here, we provide a comprehensive quantitative understanding of AML proteomic heterogeneities and hallmarks by using… read more here.
Keywords: myelogenous leukaemia; heterogeneities hallmarks; analysis; leukaemia cell ... See more keywords
Synthesis and biological evaluation of dithiocarbamate esters of parthenolide as potential anti-acute myelogenous leukaemia agents
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2018.1490734
Abstract: Abstract A series of dithiocarbamate esters of parthenolide (PTL) was designed, synthesised, and evaluated for their anti- acute myelogenous leukaemia (AML) activities. The most promising compound 7l showed greatly improved potency against AML progenitor cell… read more here.
Keywords: myelogenous leukaemia; esters parthenolide; dithiocarbamate esters; leukaemia ... See more keywords
Apoptosis induction in K562 human myelogenous leukaemia cells is connected to the modulation of Wnt/β‐catenin signalling by BHX, a novel pyrazoline derivative
Sign Up to like & getrecommendations! Published in 2018 at "Cell Proliferation"
DOI: 10.1111/cpr.12433
Abstract: The goal of this study was to explore the effects of BHX on human chronic myeloid leukaemia (CML) cells and to elucidate the underlying molecular mechanism. read more here.
Keywords: k562 human; myelogenous leukaemia; induction k562; human myelogenous ... See more keywords
Highly precise breakpoint detection of chromosome balanced translocation in chronic myelogenous leukaemia: Case series
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17500
Abstract: Chronic myelogenous leukaemia (CML) has a special phenomenon of chromosome translocation, which is called Philadelphia chromosome translocation. However, the detailed connection of this structure is troublesome and expensive to be identified. Low‐coverage whole genome sequencing… read more here.
Keywords: chronic myelogenous; translocation; myelogenous leukaemia; chromosome ... See more keywords
Persistent sacral chloroma in refractory acute myelogenous leukaemia
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Case Reports"
DOI: 10.1136/bcr-2017-219936
Abstract: Acute myelogenous leukaemia (AML) is a clonal process involving the myeloid subgroup of white blood cells. Chloromas, or myeloid sarcomas, are masses of myeloid leukaemic cells and are a unique aspect of AML. This case… read more here.
Keywords: myelogenous leukaemia; persistent sacral; chloroma refractory; sacral chloroma ... See more keywords