A novel predictive model of outcome in acute myeloid leukemia without favorable karyotype based on treatment strategy, karyotype and FLT3‐ITD mutational status
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Hematology"
DOI: 10.1002/ajh.25290
Abstract: REFERENCES 1. Greenberg PL, Tuechler H, Schanz J, et al. Revised international prognostic scoring system for myelodysplastic syndromes. Blood. 2012; 120(12):2454-2465. 2. He R, Wiktor AE, Hanson CA, et al. Conventional karyotyping and fluorescence in… read more here.
Keywords: karyotype; myeloid leukemia; acute myeloid; strategy ... See more keywords
Arginase‐1+ bone marrow myeloid cells are reduced in myeloproliferative neoplasms and correlate with clinical phenotype, fibrosis, and molecular driver
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5542
Abstract: Philadelphia‐negative myeloproliferative neoplasms (MPN) are clonal myeloid proliferative disorders characterized by sustained systemic inflammation. Despite its renowned importance, the knowledge concerning the inflammatory pathophysiology of these conditions is currently limited to studies on serum cytokines,… read more here.
Keywords: bone marrow; myeloid cells; myeloid; marrow myeloid ... See more keywords
Targeted deletion of HIF-1α in myeloid cells of neonatal mice: decreased accumulation of myeloid-derived suppressor cells and altered microbiome.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250144
Abstract: The newborn's immune system is faced with the challenge of having to learn quickly to fight off infectious agents, but tolerating the colonization of the body surfaces with commensals without reacting with an excessive inflammatory… read more here.
Keywords: myeloid derived; suppressor cells; hif; myeloid ... See more keywords
An induced pluripotent stem cell t(7;12)(q36;p13) acute myeloid leukemia model shows high expression of MNX1 and a block in differentiation of the erythroid and megakaryocytic lineages
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34122
Abstract: Acute myeloid leukemia (AML) results from aberrant hematopoietic processes and these changes are frequently initiated by chromosomal translocations. One particular subtype, AML with translocation t(7;12)(q36;p13), is found in children diagnosed before 2 years of age. The… read more here.
Keywords: stem cell; leukemia; myeloid; differentiation ... See more keywords
Depletion of Collagen IX Alpha1 Impairs Myeloid Cell Function
Sign Up to like & getrecommendations! Published in 2018 at "STEM CELLS"
DOI: 10.1002/stem.2892
Abstract: The trabecular extracellular matrix (ECM) forms a three‐dimensional scaffold to stabilize the bone marrow, provide substrates for cell‐matrix interactions and retain, present or release signals to modulate hematopoietic stem and progenitor cell development. However, the… read more here.
Keywords: myeloid cell; function; myeloid; cell ... See more keywords
Myeloid cell heterogeneity in lung cancer: implication for immunotherapy
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-02916-5
Abstract: Lung is a specialized tissue where metastases from primary lung tumors takeoff and those originating from extra-pulmonary sites land. One commonality characterizing these processes is the supportive role exerted by myeloid cells, particularly neutrophils, whose… read more here.
Keywords: immunotherapy; heterogeneity; lung cancer; cancer ... See more keywords
Uterine myeloid sarcoma
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Hematology"
DOI: 10.1007/s00277-020-04065-8
Abstract: Dear Editor, A 53-year-old woman is presented with dysmenorrhea and vomiting, lasting for few months and recently worsening. Blood tests highlighted slight leukopenia (3.460 cell/mmc), anemia (10.1 g/dL), and mild lactate dehydrogenase (LDH) increase (509… read more here.
Keywords: sarcoma; myeloid sarcoma; diagnosis; disease ... See more keywords
Recent Progress in Chronic Neutrophilic Leukemia and Atypical Chronic Myeloid Leukemia
Sign Up to like & getrecommendations! Published in 2017 at "Current Hematologic Malignancy Reports"
DOI: 10.1007/s11899-017-0413-y
Abstract: Purpose of ReviewWe reviewed recent diagnostic and therapeutic progress in chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML). We summarized recent genetic data that may guide future efforts towards implementing risk-adapted therapy based… read more here.
Keywords: neutrophilic leukemia; progress chronic; myeloid; leukemia ... See more keywords
Progesterone attenuates brain inflammatory response and protects the brain from inflammation‐induced immature myeloid cells increase: 1019
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2018.11.1043
Abstract: 1018 Myeloid cells in prgenancy and in inflammatory bowel disease: lessons from mouse models Ofer Fainaru, Gili Paz, Shay Hantisteanu, Mordechai Hallak, Yuval Ginsberg, Ron Beloosesky, Zeev Weiner RambamMedical Center, Haifa, NA, Israel, Assuta Medical… read more here.
Keywords: response; myeloid cells; inflammation; inflammatory ... See more keywords
Extramedullary acute myeloid leukemia (eAML): Retrospective single center cohort study on clinico-pathological, molecular analysis and survival outcomes
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2021.102894
Abstract: Introduction extramedullary acute myeloid leukemia (eAML) is characterized by extramedullary tumor formation infiltrated by myeloid blasts, with or without maturation and effaced architecture. The clinical, genetic and molecular aspects and overall outcomes are well defined… read more here.
Keywords: leukemia eaml; extramedullary acute; myeloid leukemia; acute myeloid ... See more keywords
Molecular approaches identify a cryptic MECOM rearrangement in a child with a rapidly progressive myeloid neoplasm.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2017.12.002
Abstract: Myeloid neoplasms are a heterogeneous group of hematologic disorders with divergent patterns of cell differentiation and proliferation, as well as divergent clinical courses. Rare recurrent genetic abnormalities related to this group of cancers are associated… read more here.
Keywords: myeloid neoplasms; myeloid neoplasm; molecular approaches; mecom ... See more keywords