The Transient Receptor Potential Vanilloid 2 (TRPV2) Channel Facilitates Virus Infection Through the Ca2+‐LRMDA Axis in Myeloid Cells
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DOI: 10.1002/advs.202202857
Abstract: The transient receptor potential vanilloid 2 (TRPV2) channel is a nonselective cation channel that has been implicated in multiple sensory processes in the nervous system. Here, it is shown that TRPV2 in myeloid cells facilitates… read more here.
Keywords: trpv2; infection; myeloid cells; lrmda ... See more keywords
Targeting Splenic Myeloid Cells with Nanobiologics to Prevent Postablative Pancreatic Cancer Recurrence via Inducing Antitumor Peripheral Trained Immunity
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202413562
Abstract: Minimally invasive irreversible electroporation ablation shows promise for pancreatic cancer (PCa), but the high recurrence and metastasis rates pose a therapeutic challenge for loco‐regional ablation treatment. Immunotherapy holds promise for preventing tumor recurrence, however, its… read more here.
Keywords: myeloid cells; pca; splenic myeloid; trained immunity ... See more keywords
Precision Targeting of Myeloid Cells via Peptide Dendrimer-Lipid Nanocarriers: A Novel Platform for Potent Cancer Immunotherapies.
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DOI: 10.1002/advs.202514417
Abstract: Selective targeting of myeloid cells (MCs) holds therapeutic potential as an immuno‐oncology approach. However, MC targeting using existing gene delivery platforms faces many barriers to clinical use, such as production scalability and off‐target delivery to… read more here.
Keywords: myeloid cells; cancer; dendrimer lipid; targeting myeloid ... See more keywords
Arginase‐1+ bone marrow myeloid cells are reduced in myeloproliferative neoplasms and correlate with clinical phenotype, fibrosis, and molecular driver
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5542
Abstract: Philadelphia‐negative myeloproliferative neoplasms (MPN) are clonal myeloid proliferative disorders characterized by sustained systemic inflammation. Despite its renowned importance, the knowledge concerning the inflammatory pathophysiology of these conditions is currently limited to studies on serum cytokines,… read more here.
Keywords: bone marrow; myeloid cells; myeloid; marrow myeloid ... See more keywords
Full spectrum cytometry improves the resolution of highly autofluorescent biological samples: Identification of myeloid cells in regenerating skeletal muscles
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DOI: 10.1002/cyto.a.24568
Abstract: Autofluorescence (AF) is an intrinsic characteristic of cells caused by the presence of fluorescent biological compounds within the cell; these can include structural proteins (e.g., collagen and elastin), cellular organelles, and metabolites (e.g., aromatic amino… read more here.
Keywords: myeloid cells; highly autofluorescent; full spectrum; regenerating skeletal ... See more keywords
Comprehensive characterization of myeloid cells during wound healing in healthy and healing‐impaired diabetic mice
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Immunology"
DOI: 10.1002/eji.201948438
Abstract: Abstract Wound healing involves the concerted action of various lymphoid and in particular myeloid cell populations. To characterize and quantitate different types of myeloid cells and to obtain information on their kinetics during wound healing,… read more here.
Keywords: wound healing; myeloid cells; healing impaired; mice ... See more keywords
Novel potent liposome agonists of triggering receptor expressed on myeloid cells 2 phenocopy antibody treatment in cells
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DOI: 10.1002/glia.24252
Abstract: The receptor Triggering Receptor Expressed on Myeloid cells 2 (TREM2) is associated with several neurodegenerative diseases including Alzheimer's Disease and TREM2 stimulation represents a novel therapeutic opportunity. TREM2 can be activated by antibodies targeting the… read more here.
Keywords: trem2; receptor expressed; triggering receptor; myeloid cells ... See more keywords
Shaping the immune‐suppressive microenvironment on tumor‐associated myeloid cells through tumor‐derived exosomes
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DOI: 10.1002/ijc.34921
Abstract: Tumor‐associated myeloid cells (TAMCs) play a crucial role in orchestrating the dynamics of the tumor immune microenvironment. This heterogeneous population encompasses myeloid‐derived suppressor cells, tumor‐associated macrophages and dendritic cells, all of which contribute to the… read more here.
Keywords: myeloid cells; cells tumor; microenvironment; tumor associated ... See more keywords
Mechanisms of HIV‐1 cell‐to‐cell transfer to myeloid cells
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DOI: 10.1002/jlb.4mr0322-737r
Abstract: In addition to CD4+ T lymphocytes, cells of the myeloid lineage such as macrophages, dendritic cells (DCs), and osteoclasts (OCs) are emerging as important target cells for HIV‐1, as they likely participate in all steps… read more here.
Keywords: cell; cell cell; myeloid cells; cell transfer ... See more keywords
T cells dominate peripheral inflammation in a cross‐sectional analysis of obesity‐associated diabetes
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DOI: 10.1002/oby.23528
Abstract: Myeloid cells dominate metabolic disease‐associated inflammation (metaflammation) in mouse obesity, but the contributions of myeloid cells to the peripheral inflammation that fuels sequelae of human obesity are untested. This study used unbiased approaches to rank… read more here.
Keywords: inflammation; peripheral inflammation; myeloid cells; dominate peripheral ... See more keywords
Cancer Stem Cells in the Immune Microenvironment.
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DOI: 10.1007/978-981-32-9620-6_12
Abstract: Cancer stem cells are a subpopulation of cancer cells responsible for the most demanding and aggressive cancer cell phenotypes: therapy resistance, a self-protective feature of stem cells; distant metastasis, requiring anchorage independence for survival in… read more here.
Keywords: cancer stem; myeloid cells; biology; cancer ... See more keywords